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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA1B
All Species:
9.39
Human Site:
S492
Identified Species:
20.67
UniProt:
P35368
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35368
NP_000670.1
520
56836
S492
P
G
T
D
G
G
A
S
N
G
G
C
E
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q28524
418
44639
F396
P
A
P
R
S
P
G
F
A
S
G
S
T
G
L
Dog
Lupus familis
XP_536449
618
67286
A498
N
K
S
D
P
V
A
A
K
G
R
R
S
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P97717
514
56400
S486
P
G
T
E
G
D
A
S
N
G
G
C
D
T
T
Rat
Rattus norvegicus
P15823
515
56567
S487
P
G
T
E
G
D
T
S
N
G
G
C
D
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506393
511
56733
G480
H
L
G
L
S
G
H
G
S
S
S
N
G
A
C
Chicken
Gallus gallus
XP_414483
507
56995
A481
H
I
A
A
S
S
Q
A
S
S
N
G
D
H
E
Frog
Xenopus laevis
O42574
385
43291
V363
S
R
Y
S
G
G
F
V
N
S
L
D
T
N
A
Zebra Danio
Brachydanio rerio
XP_001922013
544
60273
Q472
A
G
G
P
R
L
S
Q
K
T
A
T
I
A
G
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
Y401
S
L
L
N
P
I
I
Y
A
Y
F
N
K
D
F
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203873
574
63580
S527
L
C
S
S
P
S
H
S
S
K
N
P
E
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
32.1
76.8
N.A.
94.8
94.6
N.A.
77.6
70.9
28
54
25.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
N.A.
46.7
79.1
N.A.
96.3
96.5
N.A.
82.8
78.8
43.4
64.3
42.6
N.A.
N.A.
N.A.
49.6
P-Site Identity:
100
N.A.
13.3
26.6
N.A.
66.6
60
N.A.
13.3
0
26.6
13.3
0
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
13.3
40
N.A.
80
73.3
N.A.
20
20
26.6
20
13.3
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
0
0
28
19
19
0
10
0
0
28
28
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
28
0
0
10
% C
% Asp:
0
0
0
19
0
19
0
0
0
0
0
10
28
10
0
% D
% Glu:
0
0
0
19
0
0
0
0
0
0
0
0
19
0
10
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
10
% F
% Gly:
0
37
19
0
37
28
10
10
0
37
37
10
10
10
10
% G
% His:
19
0
0
0
0
0
19
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
0
0
0
10
10
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
19
10
0
0
10
0
0
% K
% Leu:
10
19
10
10
0
10
0
0
0
0
10
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
37
0
19
19
0
10
0
% N
% Pro:
37
0
10
10
28
10
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
10
10
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
19
0
19
19
28
19
10
37
28
37
10
10
10
10
10
% S
% Thr:
0
0
28
0
0
0
10
0
0
10
0
10
19
19
19
% T
% Val:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _